Why etbr is used in electrophoresis even though it is carcinogenic?
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✔Ethidium bromide is used in gel electrophoresis as a florescent tag, It gives out an intense orange colour upon binding with DNA and helps in easy detection of separated DNA fragments.
✔Though its use has been limited nowadays due to its mutation causing or carcinogenic properties.
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✔Ethidium bromide is used in gel electrophoresis as a florescent tag, It gives out an intense orange colour upon binding with DNA and helps in easy detection of separated DNA fragments.
✔Though its use has been limited nowadays due to its mutation causing or carcinogenic properties.
Answered by
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Why etbr is used in electrophoresis even though it is carcinogenic?
Answer:
Because ethidium bromide can bind with DNA, it is highly toxic as a mutagen. It may potentially cause carcinogenic or teratogenic effects, although no scientific evidence showing either health effect has been found. Exposure routes of ethidium bromide are inhalation, ingestion, and skin absorption.
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