Why galbriel pthalamide synthesus not preferred dor aromatic primary amine?
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Why cannot aromatic primary amines be prepared by Gabriel phthalimide synthesis? ANS. ... It involves nucleophilic substitution (S N 2) of alkyl halides by the anion formed by the phthalimide. But aryl halides do not undergo nucleophilic substitution with the anion formed by the phthalimide.
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