why glycolysis not occur in single step
Answers
Answer:
Outcomes of Glycolysis
If the cell cannot catabolize the pyruvate molecules further, it will harvest only two ATP molecules from one molecule of glucose. ... The last step in glycolysis will not occur if pyruvate kinase, the enzyme that catalyzes the formation of pyruvate, is not available in sufficient quantities.
Steps 1 and 3 of glycolysis are bypassed by gluconeogenesis because the glycolytic steps involve transferring a phosphate group from ATP, and gluconeogenesis can't regenerate ATP. Step 10 of glycolysis is bypassed by gluconeogenesis to work around an irreversible reaction and to avoid a futile cycle.
Explanation:
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Answer:
This step, one of the two substrate-level phosphorylation steps, requires ADP; thus, when the cell has plenty of ATP (and little ADP), this reaction does not occur. Because ATP decays relatively quickly when it is not metabolized, this is an important regulatory point in the glycolytic pathway.