Question

Why is difficult to make vaccine for influenza

Answer 1

Despite the obvious efficacy of both killed and live influenza virus vaccines, there is room for new developments. Among the critical issues in developing new and better vaccines are the following: price per dose, speed of production, ease of production, choice of substrates to grow the virus in or to express viral antigens, cross-protection for variant strains, efficacy in general and in immunologically naive populations, safety, and acceptance by the regulatory agencies and the public.

Answer 2

Answer:

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Explanation:

FDA regulatory requirements now allow influenza vaccine viruses to be grown in chicken eggs or cells. Today, the majority influenza vaccines are still grown in chicken eggs. Some influenza viruses, like H3N2 viruses, grow poorly in eggs, making it challenging to obtain good candidate vaccine viruses at times.