Question

Why is DNA molecule considered as a negatively charged molecule​

Answer 1

Answer:

The phosphate backbone of DNA is negatively charged due to the bonds created between the phosphorous atoms and the oxygen atoms. Each phosphate group contains one negatively charged oxygen atom, therefore the entire strand of DNA is negatively charged due to repeated phosphate groups.

Explanation:

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Answer 2

Explanation:

The phosphate groups that make up the sugar-phosphate backbone are responsible. You might be interested to read that molecular biologists capitalize on this property of DNA to isolate DNA fragments of differing sizes. Because DNA is negatively charged, molecular biologists often use agarose gel electrophoresis to separate different sized DNA fragments when DNA samples are subjected to an electric field — due to their negative charge, all of the DNA fragments will migrate toward the positively charged electrode, but smaller DNA fragments will migrate at a faster pace than larger DNA fragments. This simple, yet powerful, technique allows researchers to isolate DNA fragments of different sizes.