why is it important for the nuclear membrane to disintegrate in mitosis
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Answer:
The spindle fibers either form within the membrane, or penetrate it without tearing it apart. In other eukaryotes (animals as well as plants), the nuclear membrane must break down during the prometaphase stage of mitosis to allow the mitotic spindle fibers to access the chromosomes inside.
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Explanation:
The disassembly of nuclear envelope is triggered by the cyclin‐dependent kinase at the onset of mitosis. Phosphorylation of INM proteins disrupts their interaction with chromatin. Nuclear envelope breakdown is essential for sister chromatid segregation.
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