Question

Why is oxaloacetate converted to malate only in gluconeogenesis?

Answer 1

Oxaloacetate must be converted to malate in order to transport NADH reducing equivalents from the mitochondrion to the cytosol. ... Therefore, the oxaloacetateproduced via the lactate pathway can be directly converted into PEP and transported into the cytosol where it continues through thegluconeogenesis pathway.