Why is pilocarpine contraindicated in inflammatory glaucoma?
Answers
Answer:
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Pilocarpine has been commonly used in the past to lower the intraocular pressure. Pilocarpine is a potent miotic and is available as a solution or gel. Pilocarpine should be administered 3–4 times/day and is usually used in combination with other antiglaucoma drugs including beta-adrenergic blockers, adrenergics, and systemic carbonic anhydrase inhibitors. Pilocarpine is seldom used today as an ocular hypotensive agent because it irritates the ocular surface and induces uveitis, and more effective medications are readily available. Pilocarpine is also contraindicated in uveitis and secondary glaucoma because its miotic effect may predispose to posterior synechiae and pupillary occlusion. A frequently observed side effect after prolonged use is conjunctival hypersensitivity which warrants dilution of the pilocarpine or discontinuance of this drug. Despite its diminished usage in the therapy of glaucoma in the dog and cat, topical pilocarpine is still used occasionally in the therapy of neurogenic keratoconjunctivitis sicca, and in the pharmacologic diagnosis of some parasympathetic ocular neuropathies.
Explanation:
A group of eye conditions that can cause blindness.
With all types of glaucoma, the nerve connecting the eye to the brain is damaged, usually due to high eye pressure.