Why is secondary constriction formed ?
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Nuclear Structure and Dynamics.
Ultimately, the fibrillar centers alone remain associated with the mitotic chromosomes, forming what are termed nucleolus-organizing regions (NORs [Fig. 9.3B]), which often form a prominent secondary constriction of the chromosome. (The primary constriction is the centromere.)
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Due to secondary constriction, a knob-like structure is formed at the end of the chromosome called a satellite chromosome (SAT chromosome).
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