Question

Why is Tetramethyl silane used as a reference in NMR Spectroscopy? Reactive Unreactive Stable Both reactive and stable Both unreactive and stable

Answer 1

Answer:

Tetramethylsilane became the established internal reference compound for 1H NMR because it has a strong, sharp resonance line from its 12 protons, with a chemical shift at low resonance frequency relative to almost all other 1H resonances. Thus, addition of TMS usually does not interfere with other resonances.

Explanation:

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