Question

why lipids come under acid insoluble fraction?

Answer 1

Lipids are indeed small molecular weight compounds and are present not only as such but also arranged into structures like cell membrane and other membranes. when we grind a tissue, we are disrupting the cell structure. cell membrane and membranes are broken into pieces, and form vesicles which are not soluble in water. Therefore, these membrane fragments in the form of vesicles get separated along with the acid insoluble pool and hence in the macromolecular fraction. But Lipids are not strictly macromolecules.i.e., they can also be a part of micromolecules.

Answer 2

THE size of the lipids are much smaller as compared with macro. In compound it present as cell and membrane like structure and are insoluble in acids . all the acids are either ionic or they insoluble in them.

That's why lipids come under acid insoluble fraction although it is a micromolecule.

Hope it helps you!!!