why lysosomes are called suicidal bag
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heya mate ☺
50 years ago, Christian de Duve introduced the term “suicide bags” to describe lysosomes (1), the organelles containing numerous hydrolases, which were, until the discovery of the ubiquitin-proteasome system, thought to be responsible for the major part of the intracellular turnover of proteins and other macromolecules .
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Lysosomes are called suicide bags of the cell... If the cell is damaged, the lysosomes undergo autolysis and burst open. This results in the replace of those hydrolytic enzymes the released enzymes then digest their own cell and ultimately the cell dies. Hence, they are called as suicide bags of the cell.
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