Question

Why members of a family have some similarities and differences ? ​

Answer 1

Answer:

Because relatives share family environment as well as heredity, familial resemblance can be due to environmental influences as well as to hereditary influences. In other words, a portion of environmental influence could be shared by relatives, making them similar to one another.

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Answer 2

Answer:

One of the goals of structural genomics is to obtain a structural representative of almost every fold in nature. A recent estimate suggests that 70%–80% of soluble protein domains identified in the first 1000 genome sequences should be covered by about 25,000 structures—a reasonably achievable goal. As no current estimates exist for the number of membrane protein families, however, it is not possible to know whether family coverage is a realistic goal for membrane proteins. Here we find that virtually all polytopic helical membrane protein families are present in the already known sequences so we can make an estimate of the total number of families. We find that only ∼700 polytopic membrane protein families account for 80% of structured residues and ∼1700 cover 90% of structured residues. While apparently a finite and reachable goal, we estimate that it will likely take more than three decades to obtain the structures needed for 90% residue coverage, if current trends

Explanation:

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