why mosquitoes do not spread AIDS?
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Because human immunodeficiency virus (HIV) is a blood-borne pathogen, concerns have been raised about the possible transmission of HIV by blood-feeding arthropods. Laboratory studies and epidemiologic surveys indicate that this possibility is extremely remote. For biological transmission, the virus must avoid digestion in the gut of the insect, recognize receptors on and penetrate the gut, replicate in insect tissue, recognize and penetrate the insect salivary glands, and escape into the lumen of the salivary duct. In one study by Webb and colleagues, the virus persisted for 8 d in bedbugs
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