Question

Why position the rna linkage for a line nucleophilic attack(alpha) and fully deprotonate the 2' oxygen nucleophile that can exceed the maximum possible for enzyme to promote an internal phosphoester transfer reaction with a measured rate constant?

Answer 1

Answer:

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Explanation:

First, and most obvious, RNA polymerase catalyzes the linkage of ribonucleotides, not ... The polymerase unwinds the DNA at the position at which transcription!