Why revaccination is necessary inspite of development of memory b cells ?
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Memory B cells are able to persist in the human body over decades [128–131]. Thereby, they are maintaining memory for a given antigen without the need of constant antigenic stimulation or proliferation [132,133]. Memory B cells are highly abundant in the human spleen, and they make up 45% of the total B cell population in this organ [134,135].
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