Question

Why secondary and tertiary amines cannot be prepared by gabriel phthalimide synthesis?

Answer 1

because there is no any other places for nitrogen
therefore it attack on terminal position and after hydrolysis ony primary amine is obtained

Answer 2

As over alkylation is not possible in secondary and tertiary amines, they cannot be prepared by Gabriel phthalimide synthesis.

Explanation:

• The process called Gabriel synthesis is used for the preparation of primary amines.
• In this method, compound called phthalimide is made to react with ethanoic potassium hydroxide.
• This reaction leads to the formation of phthalimide potassium salt.
• When this salt is heated primary amines are produced.
• As secondary and tertiary amines don't show reaction with alkyl agent due to which over alkylation is not possible.
• Thus preparation of secondary amines and tertiary amines is not possible through Gabriel phthalimide synthesis.

Learn more about Gabriel phthalimide synthesis.

Gabriel phthalimide reaction is used for the preparation of

https://brainly.in/question/8903758

Amine that can't be prepare by Gabriel phthalimide synthesis:

Aniline

Benzyl amine

Methyl amine

Iso butylamine

Tertiary butylamine

please explain

https://brainly.in/question/3187041