Biology, asked by sabika8262, 1 year ago

Why transcription not requires any topoisomerase?

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Answered by BibhuPrasad

During DNA replication and transcription, DNA becomes overwound ahead of a replication fork. If left unabated, this torsion would eventually stop the ability of DNA or RNA polymerases involved in these processes to continue down the DNA strand. ... Topoisomerases are isomerase enzymes that act on the topology of DNA.

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