Question

Why, when graphing ligand concentration vs. the percentage of receptors bound, do we not achieve 100% receptor binding under normal circumstances?

Answer 1

Yes, the hundred percent receptor binding under usual conditions is not possible, according to the ligand concentration versus the percentage of receptor-bound because of negative physiological response and steric hindrance. The binding of ligand does the steric hindrance when binds with receptor at the maximum levels.

Answer 2

Yes, the hundred percent receptor binding under usual conditions is not possible, because according to the ligand concentration versus the percentage of receptor-bound because of negative physiological response and steric hindrance. The binding of ligand faces the steric hindrance when binds with receptor at the maximum levels.