Williamson's synthesis can be occurred at best in which of the following solvent?
1. H20
2. H2O/HF
3. EtOH/H+
4. Et20
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Explanation:
The Williamson ether synthesis is an SN2 reaction in which an alkoxide ion is a nucleophile that displaces a halide ion from an alkyl halide to give an ether.The Williamson ether synthesis is an organic reaction, forming an ether from an organohalide and a deprotonated alcohol (alkoxide). ... An example is the reaction of sodium ethoxide with chloroethane to form diethyl ether and sodium chloride: [Na]+[C2H5O]− + C2H5Cl → C2H5OC2H5 + [Na]+[Cl]
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