Write a note on aldol condensation
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An aldol condensation is acondensation reaction in organic chemistry in which an enol or an enolate ion reacts with a carbonyl compound to form a β-hydroxyaldehyde or β-hydroxyketone (an aldol reaction), followed by dehydration to give a conjugated enone.
Aldol condensations are important in organic synthesis, because they provide a good way to form carbon–carbon bonds.For example, the Robinson annulation reaction sequence features an aldol condensation;the Wieland–Miescher ketone product is an important starting material for many organic syntheses.Aldol condensations are also commonly discussed in university level organic chemistry classes as a good bond-forming reaction that demonstrates important reaction mechanisms.
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An aldol condensation is acondensation reaction in organic chemistry in which an enol or an enolate ion reacts with a carbonyl compound to form a β-hydroxyaldehyde or β-hydroxyketone (an aldol reaction), followed by dehydration to give a conjugated enone.
Aldol condensations are important in organic synthesis, because they provide a good way to form carbon–carbon bonds.For example, the Robinson annulation reaction sequence features an aldol condensation;the Wieland–Miescher ketone product is an important starting material for many organic syntheses.Aldol condensations are also commonly discussed in university level organic chemistry classes as a good bond-forming reaction that demonstrates important reaction mechanisms.
×=×=×=×=×=×=×=×=×=×=×=×=×
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Aldol Condensation
- An aldol condensation is defined as a condensation reaction in organic chemistry where two carbonyl moieties that are of aldehydes or ketones get into a reaction to form a β-hydroxy aldehyde or β-hydroxy ketone known as an aldol reaction, and this is then pursued by dehydration to provide a conjugated enone.
- Aldol condensations are significant in organic synthesis and biochemistry as a means to develop carbon-carbon bonds
- In its normal form, it encompasses the nucleophilic addition of a ketone enolate to an aldehyde to create a β-hydroxy ketone or "aldol" (aldehyde + alcohol) which is a structural unit base in several generally arising molecules and pharmaceuticals.
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