Question

Write a note on primary amd secondarystructureof proteins

Answer 1

Primary structure of proteins: Refers to sequence of amino acids linked together through peptide bonds in a polypeptide chain. It also refers to position of disulphide bonds (-S-S) that are formed between the -SH groups of cysteine residues that are adjacent in space but not in the linear sequence of amino acids

Secondary structure of proteins: The polypeptide chain undergoes regular folding or coiling to give rise secondary structure of protein. The coiling of polypeptide chain is produced and stabilized by weak, low energy non-covalent hydrogen bonds and covalent disulpide bonds. Each hydrogen bond is weak, but collectively hydrogen bonds are strong enough to stabilize the secondary structure. The two most prominent types of secondary structure of proteins are (i) alpha-Helix & (ii) beta-Pleated sheet.

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