Write a short note on carcinogenic compounds
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- Several polycyclic aromatic compounds are toxic and carcinogenic.
- eg. Benzene is oxidized to an epoxide, benzopyrene, in liver Benzopyrene is converted into epoxydiol.
- These substances can react with DNA and induce mutation leading to uncontrolled growth of certain cells. In this way, they cause cancer in the body.
- Carcinogenic compounds are produced by incomplete combustion of tobacco, coal and petroleum. Hence tobacco, coal are called cancer causing substances (carcinogenic substances).
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A carcinogen is any substance, radionuclide, or radiation that promotes carcinogenesis, the formation of cancer. This may be due to the ability to damage the genome or to the disruption of cellular metabolic processes.
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