Question

Write a short note on Humburger's phenomena or chloride shift​

Answer 1

Answer:

Hamburger’s Phenomenon – Chloride Shift by Hartog Jacob Hamburger.

• Exchange of Negative Ions which maintains electrical balance between Plasma and RBC cytosol

• Diffusion of HCO3⁻ (Bicarbonate) ions from RBCs to plasma, Develops charge imbalance in RBCs

• To maintain the charge neutrality, Cl ions enters the RBCs

Answer 2

• Hamburger's phenomenon that - chloride shift pertains to the dispersion of chloride ions into the RBCs to conserve the ionic equilibrium between the RBCs and the plasma.

• The ratio of construction of carbonic acid inside the RBC is very elevated as distinguished from its construction in the plasma. Carbonic acid is uncertain and almost instantly dissociates into HCO3- and H+ in the existence of the enzyme carbonic anhydrase (CA) directing to the proliferation of a huge quantity of HCO3 - inside the RBCs.
• RBCs.CO2 + H2O CA [ H2CO3 CA - H++ HCO3- It accordingly, motions out of the RBCs resulting in an inequality of the charge inside the RBCs. To conserve the ionic equilibrium between the RBCs and the plasma, Cl diffuses into the RBCs.

#SPJ2