Question

write a short note on necrosis. ​

Answer 1

Answer:

Necrosis in the setting of acute lung injury can be seen in infections, infarction, and acute aspiration. Necrosis can involve lung parenchyma alone or occur with necrosis of airway epithelium .

Influenza, herpes simplex, varicella-zoster, and adenovirus pneumonias are all infections characterized by DAD with necrosis, and some can be easily recognized by characteristic viral cytopathic effects such as intranuclear inclusions (herpes simplex, varicella-zoster) or smudge cells (adenovirus). Some bacterial and fungal infections can also produce necrosis.

Although lung infarction and acute aspiration pneumonia are localized rather than diffuse processes, they can be seen in a background of DAD and demonstrate necrosis. Malignancies can also present with associated areas of DAD, and necrosis can be prominent in these cases.

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