Question

Write a short note on the enzymes and toxins.​

Answer 1

Other bacterial enzymes are hemolysins. These enzymes destroy red blood cells. Streptococci, staphylococci, and certain Clostridium species produce hemolysins. ... Hyaluronidase destroys hyaluronic acid, a polysaccharide that “cements” cells together in a tissue.

Answer 2

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Enzymes

Many pathogens produce a series of enzymes to help overcome body defenses and establish themselves in the host. One example is leukocidins, a group of enzymes that destroy white blood cells. This destruction lessens the body's ability to perform phagocytosis. Other bacterial enzymes are hemolysins. These enzymes destroy red blood cells. Streptococci, staphylococci, and certain Clostridium species produce hemolysins.  Coagulases are bacterial enzymes that clot the blood. These enzymes convert fibrinogen into fibrin, which forms the threads of a blood clot. The clot helps staphylococci avoid the body's phagocytes and contributes to its pathogenicity.  Hyaluronidase destroys hyaluronic acid, a polysaccharide that “cements” cells together in a tissue. Hyaluronidase thus permits organisms to spread through tissues and establish themselves at sites distant from that of the intial infection. Another enzyme, called collagenase, breaks down collagen in the connective tissues of muscles. It thereby encourages the spread of infection.

Toxins

Many bacteria are able to produce poisonous substances called toxins. Toxins act on the body's cells, tissues, and organs and interfere with important body processes, thereby interrupting normal body functions. Those microorganisms that produce toxins are said to be toxigenic. The condition in which toxins are produced is called toxemia.

Two important types of toxins are exotoxins and endotoxins. Exotoxins are proteins produced by bacteria during their growth and liberated into their surrounding environment. Exotoxins are produced chiefly by Gram‐positive bacteria, and the genes for this production are carried primarily on the plasmids.

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