write about Conversion of pyruvic acid to Acetyl CoA
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This is an oxidative decarboxylation reaction. It is catalyzed by a multienzyme complex - pyruvate dehydrogenase complex (PDH). This enzyme is present in mitochondria of eukaryotes and cytosol of prokaryotes.
This reaction is called as 'connecting link reaction between glycolysis and Krebs cycle.
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