write an article on the present scenario of the world Suitation due to the pandemic
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World Health Organization (WHO) is concerned about the pandemic of Coronavirus (COVID-19) and controls its spreading at the high end. The International Association of Advanced Materials (IAAM) intends to provide forum for high-tech healthcare. In the current scenario, IAAM called a multi-lateral consortium to developed medical technology to control the spreading of COVID-19 with the help of the interdisciplinary experts from multiple countries. This innovation is perpetuated to create multi-lateral cooperation in the area of ‘healthcare innovation and technology’. Adaptation of advanced technologies and their logical integration according to contemporary healthcare measures could be a smart strategy for epidemic management activities. Establishing an advanced phenotype model for prognosis is an important step in the prevention of infectious disease management such as COVID-19. This article has overviewed the global situation, efforts, and prospective of coronavirus pandemic.
The worldwide threat of Coronaviruses (CoV) based epidemics and the latest outbreak in China created several complications in current healthcare practices in terms of prognosis and prevention. CoV have been, characterized by enveloped non-segmented positive-sense RNA viruses, which belong to the family Coronaviridae and the order Nidovirales, identified since the 1960’s as a human pathogen . The CoV pathogens are common in many different types of animals including camels, cats, cows, bats, horse, and human. In humans, till now seven types of coronaviruses have been reported, out of which four types (229E, NL63, OC43, and KHU1) are causing mild to moderate respiratory infections, like the common cold. Another two types, Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) and Middle East Respiratory Syndrome coronavirus (MERS-CoV), can cause severe respiratory infections, while, the seventh type (Novel coronavirus or COVID-19) is a new coronavirus recently discovered in China . In humans, COVID-19 cause illness mostly through respiratory or gastrointestinal infections, where symptoms can range from the common cold to more severe lower respiratory infections such as pneumonia . Mainly person to person contact can impart more disease burden .
Human coronavirus outbreaks (SARS-CoV and MERS-CoV) have caused more than 10 thousand cumulative cases in the past two decades, with mortality rates of 10% for SARS-CoV and 37% for MERS-CoV [1]. In general, different types of human coronaviruses vary in the severity of illness, their cause, and how far they can spread. Although drug repositioning and large spectra therapies are under evaluation, at present, no specific treatment is outlined for COVID-19. Risk of coronavirus outbreaks spread rapidly due to its ubiquitous presence and zoonotic mode of transmission through various host species , which makes it further complex pathogen.
Ideally, disease-associated biomarkers should be needed to identify infections with high sensitivity, specificity, reliability with rapidness and cost effectively to detect viruses. Studies related to immuno-sensing of bacteria or biomolecules and electrochemical biosensing of molecules through use of advanced material science have already established the biosensor research at next level . Bioelectronic research on molecular switching through dynamic function leads towards possibility of advanced virus research, which can strengthen more efficiently to the prognosis strategies . The gradual decline in the cost of sequencing genomes in trend studies, diagnostics, and real-time surveillance is helpful for rapid detection of disease outbreaks and understanding its mechanism.
Digitalization due to advent of technologies will open opportunities for fast, accurate, distant diagnosis and delivery models. For mass level effectiveness, many precise wireless devices could be integrated to build the digital medicine type model for coronavirus . Considering the recent technological advances, we have proposed to use an advanced technological model for better results. This model includes integration of latest technology of biosensors, Internet of things, and artificial intelligence (IoT and AI) along with clinical phenotype models for various CoV phenotypes (SARS-CoV, MERS-CoV, COVID-19, etc.). If coronavirus infections are not properly controlled, public health management will decline and global trades along with economy will suffer. This article deals with hosts’ adaptability and pathogens variability to counterbalance the challenges against prognosis and preventive measures and produce a fundamental model to combat disease burden and viral infections in the scope of human health.
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