Question

Write down various physiological and biochemical functions of Vitamin D​

Answer 1

Explanation:

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The vitamin D endocrine system plays an important role in the maintenance of normal calcium homeostasis. Abnormalities of this system occur in many conditions, such as rickets, osteomalacia, hypoparathyroidism, and hyperparathyroidism.

In addition to causing mineralization of the skeleton and increasing serum calcium and phosphorus concentrations, vitamin D is known to regulate parathyroid growth and parathyroid hormone production; it plays a role in the islet cells of the pancreas, has a significant effect on the immune system

Answer 2

Answer:

Vitamin D3 is a prohormone produced in skin through ultraviolet irradiation of 7-dehydrocholesterol. It is biologically inert and must be metabolized to 25-hydroxyvitamin D3 in the liver and then to 1α,25-dihydroxyvitamin D3 in the kidney before function. The hormonal form of vitamin D3, ie, 1α,25-dihydroxyvitamin D3, acts through a nuclear receptor to carry out its many functions, including calcium absorption, phosphate absorption in the intestine, calcium mobilization in bone, and calcium reabsorption in the kidney. It also has several noncalcemic functions in the body. This overview provides a brief description of the physiologic, endocrinologic, and molecular biologic characteristics of vitamin D. It also provides information on new selective analogs of 1α,25-dihydroyvitamin D3 for therapy.

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