Write note on recombinant vaccines. Explain one in detail.
Answers
Recombinant DNA technology in recent years has become a boon to produce new generation vaccines. By this approach, some of the limitations (listed above) of traditional vaccine production could be overcome. In addition, several new strategies, involving gene manipulation are being tried to create novel recombinant vaccines.
Types of Recombinant Vaccines:
The recombinant vaccines may be broadly categorized into three groups:
1. Subunit recombinant vaccines:
These are the components of the pathogenic organisms. Subunit vaccines include proteins, peptides and DNA.
2. Attenuated recombinant vaccines:
These are the genetically modified pathogenic organisms (bacteria or viruses) that are made non-pathogenic and used as vaccines.
3. Vector recombinant vaccines:
These are the genetically modified viral vectors that can be used as vaccines against certain pathogens.
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