Write principle and experimental setup of protein x-ray crystallography?
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▶ principle and experimental setup of protein x-ray crystallography are given below :-
- Protein X‐ray crystallography has affected drug discovery in (a) the identification of new drug targets, (b) the understanding of molecular target mechanisms, and (c) the discovery of new lead compounds. The integration of protein X‐ray crystallography into the early discovery process by joining it with chemical synthesis and assaying has become a very effective tool for lead optimization.
- This article aims to familiarize scientists with X‐ray protein crystallographic techniques and their exemplified application for the purpose of drug discovery.
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X-ray crystallography (XRC) is the experimental science determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract into many specific directions.
JAI SHRI RAM
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