Write short note on Anti-pyratic drugs. (50 words)
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Antipyretics (/ænti.paɪˈrɛ.tɪks/, from anti- 'against' and pyretic 'feverish') are substances that reduce fever.[1] Antipyretics cause the hypothalamus to override a prostaglandin-induced increase in temperature. The body then works to lower the temperature, which results in a reduction in fever.
Most antipyretic medications have other purposes. The most common antipyretics in the United States are ibuprofen and aspirin, which are nonsteroidal anti-inflammatory drugs (NSAIDs) used primarily as analgesics(pain relievers), but which also have antipyretic properties; and acetaminophen(paracetamol), an analgesic with weak anti-inflammatory properties.[2]
There is some debate over the appropriate use of such medications, as fever is part of the body's immune response to infection.[3][4] A study published by the Royal Society claims fever suppression causes at least 1% more influenzacases of death in the United States, which results in at least 700 extra deaths per year.[5]
Most antipyretic medications have other purposes. The most common antipyretics in the United States are ibuprofen and aspirin, which are nonsteroidal anti-inflammatory drugs (NSAIDs) used primarily as analgesics(pain relievers), but which also have antipyretic properties; and acetaminophen(paracetamol), an analgesic with weak anti-inflammatory properties.[2]
There is some debate over the appropriate use of such medications, as fever is part of the body's immune response to infection.[3][4] A study published by the Royal Society claims fever suppression causes at least 1% more influenzacases of death in the United States, which results in at least 700 extra deaths per year.[5]
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1. effective against fever; called also antifebrile.
2. something having this effect, such as a cold pack, aspirin, or quinine; antipyretic drugs dilate the blood vessels near the surface of the skin, thereby allowing more blood to flow through the skin, where it can be cooled by the air. An antipyretic can also increase perspiration, the evaporation of which cools the body. Called also febricide and febrifuge.
2. something having this effect, such as a cold pack, aspirin, or quinine; antipyretic drugs dilate the blood vessels near the surface of the skin, thereby allowing more blood to flow through the skin, where it can be cooled by the air. An antipyretic can also increase perspiration, the evaporation of which cools the body. Called also febricide and febrifuge.
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