write the functional activity of centromere
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Centromeres play essential roles in equal chromosome segregation by directing the assembly of the microtubule binding kinetochore and serving as the cohesion site between sister chromatids.
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- The primary function of the centromere is to provide the foundation for assembly of the kinetochore, which is a protein complex essential to proper chromosomal segregation during mitosis. In electron micrographs of mitotic chromosomes, kinetochores appear as platelike structures composed of several layers
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