write three characteristics of cancerous cells
Answers
Three characteristics of cancerous cells.
- Self-sufficiency in growth signals.
- Limitless replicative potential.
- Tissue invasion and metastasis.
Answer:
Cancer cells
one of the fundamental features of cancer is tumor clonality (the tumors development from single cell)
increased ability to survive (they often gain resistance to apoptosis)
aberrant regulation of cell cycle (mainly is affected transition between G1- and S-phase)
grow and divide at an abnormally rapid rate
decreased need of hormones and growth factors
coming from outside of the cell
poorly differentiated
abnormal membranes, cytoskeletal proteins, and morphology
a high number of chromosomal breaks and numerous chromosomal aberrations
presence of so-called tumor neoantigens
some transformed cells have ability of autocrine stimulation (usually via growth factors)
intercellular communication and the relationship between tumor cells and neighboring cells is disrupted
a failure to fix to a solid cell surface.
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