Question

ᴡʜᴀᴛ ᴀʀᴇ ᴛʜᴇ ᴛᴏxɪᴄɪᴛɪᴇꜱ ᴏꜰ ᴀᴍɪᴏᴅᴀʀᴏɴᴇ?​

Answer 1

The three main complications of long-term amiodarone use are pulmonary toxicity, thyroid disease and liver toxicity. Pulmonary toxicity progresses slowly in the setting of amiodarone use, may be subtle initially and is the most common cause of death related to amiodarone therapy.

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Answer 2

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• The three main complications of long-term amiodarone use are pulmonary toxicity, thyroid disease and liver toxicity. 
• Pulmonary toxicity progresses slowly in the setting of amiodarone use, may be subtle initially and is the most common cause of death related to amiodarone therapy.
• Chronic toxicity (eg, chronic interstitial pneumonitis, organising pneumonia) is more common and presents gradually with symptoms including non-productive cough, dyspnoea, fever, pleuritic chest pain, fatigue and/or weight loss. Mortality has been reported as up to 10% in some studies1.

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