Question

Xenobiotics metabolism phase1 and phase 2 reaction

Answer 1

CONJUGATION REACTIONS PREPAREXENOBIOTICS FOR EXCRETION INPHASE 2 OF THEIR METABOLISM. Inphase 1 reactions, xenobiotics are generally converted to more polar, hydroxylated derivatives. In phase 2 reactions, these derivatives are conjugated with molecules such as glucuronic acid, sulfate, or glutathione.