Question

You have a myeloma protein, X, whose isotype is unknown and several other myeloma proteins of all known isotypes (e.g., IgG, IgM, IgA, IgD and IgE).

a. How could you produce isotype specific antibodies that could be used to determine the isotype of myeloma protein, X?​

Answer 1

Answer:

Multiple Myeloma (also known as Myeloma or Plasma Cell Myeloma) is a malignancy of plasma cells, which are the white blood cells responsible for the production of antibodies (proteins). Antibodies protect humans from infections. It is a cancer with a vast spectrum of presentations, ranging from an indolent (slowly developing) form to a virulent form; from a disorder with a minimal protein abnormality and only a small number of malignant plasma cells, to a cancer that can result in rapid progression and death. The disease has numerous consequences, including anemia causing fatigue, bone loss resulting in weakening of the bones, bone fractures, and pain, kidney damage sometimes resulting in the need for dialysis, high calcium levels, altered immunity resulting in infections, and nerve damage which can cause numbness, tingling, or even pain and loss of strength.

Explanation: