Question

Zoloft is available for I. M use in
strength of 0.15 mg/ml, how many
milliliters would provide a dose of 60
?microgram
0.4 ml O
0.5 ml O
0.6 ml o
0.3 ml O
​

Answer 1

Answer: Initial: 50 mg PO qDay

May increase by 25 mg at 1-week intervals; not to exceed 200 mg qDay

Initial: 50 mg PO qDay

May increase by 25 mg at 1-week intervals; not to exceed 200 mg qDay

Initial: 25 mg PO qDay

May increase by 25 mg at 1-week intervals; not to exceed 200 mg qDay

Initial: 25 mg PO qDay

May increase by 25 mg at 1-week intervals not to exceed 200 mg qDay

Initial: 50 mg qDay PO given continuously throughout menstrual cycle or given during luteal phase only

May increase by 50 mg at the onset of each new menstrual cycle; no more than 150 mg qDay when administered continuously or 100 mg qDay when administered

during luteal phase only25-100 mg daily for up to 5 years; 75-100 mg doses found to be most effective

Renal impairment: Dose adjustment not necessary

Hepatic impairment

   Mild (Child-Pugh 5-6): Decrease recommended starting dose and therapeutic dose by 50%

   Moderate-to-severe (Child-Pugh 7-15): Not recommended; sertraline is extensively metabolized, and the effects in patients with moderate and severe hepatic impairment have not been studied