1. Fructose-2, 6-biphosphate is
formed by the action of
O Phosphofructokinase-1
Phosphofructokinase-2
O
Fructose biphosphate isomerase
Fructose-1, 6-biphosphatase
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- Elevated expression of Fru-2,6-P2 levels in the liver allosterically activates phosphofructokinase 1 by increasing the enzyme's affinity for fructose 6-phosphate, while decreasing its affinity for inhibitory ATP and citrate.
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