10 disease and inventer/scientist
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1.Tania de Koning-Ward, co-author of the paper and an eminent member of Deakin’s Medical School, published her findings in Nature. She said that the research had shown that the proteins could get access to the RBC through a single entrance, which eventually provided a path to get into the RBC so that it could survive and multiply. The scientists managed to change the function of this entry point so that the proteins could not get into the RBC, and then starve and kill the parasite.
2.Gleevec, which is also known as Imatinib, is greatly considered a miracle drug to many. It was initially given an approval in 2001 by the US Food and Drug Administration to cure Chronic Myelogenous Leukemia (CML).
Recently, the results of a follow-up study which lasted for five years were outstanding. In this study, researchers found that after five years of therapy with Gleevec, 98% of patients exhibited a CHR. Furthermore, the overall survival rate after five years was 89% and the relapse rate was a mere 17%. All of these findings have proved the impressive nature of Gleevec.
3.Scientists at The Scripps Research Institute (TSRI) have devised a new strategy for the discovery of drugs that allows researchers to choose the chemical compounds that can impact cells in a technique required for the treatment of a particular disease. In order to emphasize the power of this technique, the team at TSRI used this strategy to determine a compound that has the potential to treat diabetes linked to obesity. They were also successful in identifying the fat-cell enzyme that is inhibited by the compound. Interestingly enough, this enzyme has not yet been thought to treat diabetes.
4.A research headed by the University of Dundee has enhanced the power of developing new drugs that focus on a class of enzymes involved in major diseases like neurodegenerative condition and even cancer. The research team has been targeting the class of enzymes known as deubiquitylases (DUBs). The human genome has been found to have close to 90 DUBs, which are active in every process.
5.Swiss pharmaceutical firm, Novarits, recently stated that the US Food and Drug Administration had given the breakthrough therapy status to Serelaxin, which is used in the treatment of acute heart failure. According to Novartis, the FDA’s decision was based by safety and efficacy outcomes from a late stage trial of its drug, Serelaxin. The study also proved that the drug cut down the deaths of patients by 37% at six months following acute heart failure in comparison to patients receiving standard therapy.
6. The task of getting a medication right from conception to the market is the toughest job of all. Added to this, it can consume anywhere between $1-$5 billion dollars and a decade of effort. Even then, the chances of failure seem to be high at every step. Considering the massive amount of failure rate and uncertainty, the news of Vertex Pharmaceutical’s new drug combination which can treat Cystic Fibrosis comes as a huge respite. This is a huge triumph for researchers who have been since ages trying to find a cure for this disease.
7. Multiple Sclerosis is an autoimmune disease that can cause serious harm to the spinal cord and brain. The symptoms include restricted movement and profound fatigue. It usually affects people between the ages of 20 to 50. The disease harms a fatty membrane, referred to as myelin, which safeguards nerve fibers in the central nervous system. Tim Coetzee, PhD, chief research officer of the National Multiple Sclerosis Society says that new research has opened up opportunities.
8.Recently, Africa has been plagued by the deadly Ebola virus. There has been very little scientific research breakthrough with researchers trying to unravel the mystery behind this disease. However, scientists at the Icahn School of Medicine at Mount Sinai, the University of Texas Southwestern Medical Center and Washington University in St. Louis may be able to crack the code on how this virus destroys the immune system and find out ways to prevent the disease.
9. Around 18 monkeys infected with Ebola were found to be totally cured after being administered ZMapp. The results, according to experts, were heavily encouraging. Professor Peter Piot, Director of the London School of Hygiene & Tropical Medicine, stated that these trials now have a strong backing and should be used in humans. On the other hand, it should be noted that two patients treated with the drug had died, but it may have been because the drug was administered too late for it to be effective.
10. Scientists have found a new drug that could possibly treat small cell lung cancer, the most destructive form of the disease. Currently, this drug is undergoing clinical trials and could potentially be used to treat patients who have tumours that are not affected by chemotherapy treatment.
2.Gleevec, which is also known as Imatinib, is greatly considered a miracle drug to many. It was initially given an approval in 2001 by the US Food and Drug Administration to cure Chronic Myelogenous Leukemia (CML).
Recently, the results of a follow-up study which lasted for five years were outstanding. In this study, researchers found that after five years of therapy with Gleevec, 98% of patients exhibited a CHR. Furthermore, the overall survival rate after five years was 89% and the relapse rate was a mere 17%. All of these findings have proved the impressive nature of Gleevec.
3.Scientists at The Scripps Research Institute (TSRI) have devised a new strategy for the discovery of drugs that allows researchers to choose the chemical compounds that can impact cells in a technique required for the treatment of a particular disease. In order to emphasize the power of this technique, the team at TSRI used this strategy to determine a compound that has the potential to treat diabetes linked to obesity. They were also successful in identifying the fat-cell enzyme that is inhibited by the compound. Interestingly enough, this enzyme has not yet been thought to treat diabetes.
4.A research headed by the University of Dundee has enhanced the power of developing new drugs that focus on a class of enzymes involved in major diseases like neurodegenerative condition and even cancer. The research team has been targeting the class of enzymes known as deubiquitylases (DUBs). The human genome has been found to have close to 90 DUBs, which are active in every process.
5.Swiss pharmaceutical firm, Novarits, recently stated that the US Food and Drug Administration had given the breakthrough therapy status to Serelaxin, which is used in the treatment of acute heart failure. According to Novartis, the FDA’s decision was based by safety and efficacy outcomes from a late stage trial of its drug, Serelaxin. The study also proved that the drug cut down the deaths of patients by 37% at six months following acute heart failure in comparison to patients receiving standard therapy.
6. The task of getting a medication right from conception to the market is the toughest job of all. Added to this, it can consume anywhere between $1-$5 billion dollars and a decade of effort. Even then, the chances of failure seem to be high at every step. Considering the massive amount of failure rate and uncertainty, the news of Vertex Pharmaceutical’s new drug combination which can treat Cystic Fibrosis comes as a huge respite. This is a huge triumph for researchers who have been since ages trying to find a cure for this disease.
7. Multiple Sclerosis is an autoimmune disease that can cause serious harm to the spinal cord and brain. The symptoms include restricted movement and profound fatigue. It usually affects people between the ages of 20 to 50. The disease harms a fatty membrane, referred to as myelin, which safeguards nerve fibers in the central nervous system. Tim Coetzee, PhD, chief research officer of the National Multiple Sclerosis Society says that new research has opened up opportunities.
8.Recently, Africa has been plagued by the deadly Ebola virus. There has been very little scientific research breakthrough with researchers trying to unravel the mystery behind this disease. However, scientists at the Icahn School of Medicine at Mount Sinai, the University of Texas Southwestern Medical Center and Washington University in St. Louis may be able to crack the code on how this virus destroys the immune system and find out ways to prevent the disease.
9. Around 18 monkeys infected with Ebola were found to be totally cured after being administered ZMapp. The results, according to experts, were heavily encouraging. Professor Peter Piot, Director of the London School of Hygiene & Tropical Medicine, stated that these trials now have a strong backing and should be used in humans. On the other hand, it should be noted that two patients treated with the drug had died, but it may have been because the drug was administered too late for it to be effective.
10. Scientists have found a new drug that could possibly treat small cell lung cancer, the most destructive form of the disease. Currently, this drug is undergoing clinical trials and could potentially be used to treat patients who have tumours that are not affected by chemotherapy treatment.
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