2. What are broad spectrum antibiotics?
Answers
- Broad-spectrum antibiotics are active against a wider number of bacterial types and, thus, may be used to treat a variety of infectious diseases. Broad-spectrum antibiotics are particularly useful when the infecting agent (bacteria) is unknown.
Answer:
A broad-spectrum antibiotic is an antibiotic that acts on the two major bacterial groups, gram-positive and gram-negative, or any antibiotic that acts against a wide range of disease-causing bacteria..
EXPLANATION :
There are an estimated 10–100 trillion multiple organisms that colonize the human body. As a side-effect of therapy, antibiotics can change the body's normal microbial content by attacking indiscriminately both the pathological and naturally occurring, beneficial or harmless bacteria found in the intestines, lungs and bladder. The destruction of the body's normal bacterial flora is thought to disrupt immunity, nutrition, and lead to a relative overgrowth in some bacteria or fungi. An overgrowth of drug-resistant microorganisms can lead to a secondary infection such as Clostridium difficile ("C. diff") or candidiasis ("thrush"). This side-effect is more likely with the use of broad-spectrum antibiotics, given their greater potential to disrupt a larger variety of normal human flora...
Examples of broad-spectrum antibiotics
- Aminoglycosides (except for streptomycin)
- Ampicillin.
- Amoxicillin/clavulanic acid (Augmentin)
- Azithromycin.
- Carbapenems (e.g. imipenem)
- Piperacillin/tazobactam.
- Quinolones (e.g. ciprofloxacin)
- Tetracycline-class drugs (except sarecycline)