275. Genomic expression and single-nucleotide polymorphism profiling discriminates chromophobe renal cell carcinoma and oncocytoma
Answers
hromophobe renal cell carcinoma (chRCC) and renal oncocytoma are two distinct but
closely related entities with strong morphologic and genetic similarities. While chRCC is a
malignant tumor, oncocytoma is usually regarded as a benign entity. The overlapping
characteristics are best explained by a common cellular origin, and the biologic differences
between chRCC and oncocytoma are therefore of considerable interest in terms of
carcinogenesis, diagnosis and clinical managemen
Explanation:
Carcinoma is a type of cancer that starts in cells that make up the skin or the tissue lining organs, such as the liver or kidneys. Like other types of cancer, carcinomas are abnormal cells that divide without control. They are able to spread to other parts of the body, but don't always.