3 major cellular events in drug discovery?
Answers
Drug discovery is how new medications are discovered. Historically, drugs were mostly found by identifying active ingredients from traditional medicines or purely by chance. Afterward, classical pharmacology was used to investigate chemical libraries including small molecules, natural products, or plant extracts, and find those with therapeutic effects. Since human DNA was sequenced, reverse pharmacology has found remedies to existing diseases through testing.
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Explanation:
The complexity in drug development has increased manifolds over the past 40 years, requiring preclinical testing, investigational new drug (IND) applications, and completed clinical testing before marketing approval from the FDA. Generally, new drug applications (NDAs) or biologics license applications (BLA) are reviewed comprehensively before approval, and then drug performance is resubmitted to regulatory agencies for post-marketing studies. The overarching goal is to bring more efficient and safer treatments to the patients as quickly as possible after a thorough medical evaluation.
