Question

30-year old, 70 kg male has been taking 131.12 mg of an antiviral drug daily. Because a low steady state plasma drug concentration of 3.83 mg/L was obtained, the dose was increased to 289.85 mg/day. Due to the dose increase, the steady state average drug concentration was increased to 15.03 mg/L (Vd of this antiviral drug is 066 Like and its bioavailability is 83.41 per cent) Please calculate the half life for this drug at steady state while the patient is having a dose rate of 239.49 mg/day by using the Vmax and Km values obtained using the direct linear plot method​

Answer 1

Answer:

Explanation:

because a low steady state plasma drug concentration of 3.83 mg/L was obtained the dose was increased to 289.85 mg/day. Due to the dose increase the steady state average drug concentration was increased to 15.03 mg/L (Vd of ... 1 2 points A 30 year old, 70 kg male has been taking 131.12 mg of an antiviral drug daily.

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