Question

5) What will be the condition of progeny if the marraiage between carrier women and sufferer
Man takes place?​

Answer 1

A daughter would have a 50% chance of becoming a carrier, but not actually a sufferer of the disease. This happens because a female has two X chromosomes, and since the father can only ever give an unaffected X chromosome the only possible outcomes will be that the daughter will either have two normal X chromosomes or one affected X paired with a normal X chromosome. A female would need two affected X chromosomes in order to become a hemophiliac because the gene is recessive and a normal chromosome would override it. On the other hand, a son would have a 50% chance of suffering from the disease. This happens because a male has an X chromosome, which he’d receive from the mother, paired with a Y chromosome, which he’d receive from the father. The mother has a 50% chance of giving her affected X chromosome and since there won’t be another normal X chromosome to be paired with it, there will be nothing to override the trait.
So, the correct answer is '50% sons will have haemophilia'.
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