Question

A functional allele for CFTR protein can be introduced into the epithelial cells of lungs for a person suffering with congenital cystic fibrosis. Why does this approach is not a permanent cure for cystic fibrosis

Answer 1

It is not a permanent cure because after the protein gets used up, again a new batch of protein must be introduced. So regular injections of protein is required. So it is not a permanent cure.

Answer 2

Even though the quality treatment could decrease the side effects of CF and keep further harm from happening, it can't fix scarring or other long-lasting harm that occurred preceding the treatment.

Why is it so?

• Quality treatment can't fix organ harm that has proactively happened.
• Gene treatment can be life-putting something aside for certain individuals with explicit ailments, yet it's costly and can cause side effects.
• Like numerous hereditary illnesses, a large group of various transformations can set off the condition.
• Around 90% of patients convey something like one change called ΔF508 — and one is particularly confounded to fix.

How close is a solution for cystic fibrosis?

• Indeed, even with the promising examination in progress, new medicines or solutions for CF are still logical years away.
• New medicines require long periods of examination and preliminaries before administering organizations will permit clinics and specialists to offer them to patients.

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