A new drug is developed which selectively cleaves covalent bonds between two sulfur atoms of non-adjacent amino acids in a polypeptide chain. Which level of protein structure in affected molecules would be most directly affected by the drug
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A new drug is developed which selectively cleaves covalent bonds between two sulfur atoms of non-adjacent amino acids in a polypeptide chain.
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The tertiary structure of the protein would be most directly affected by the medicine.
Explanation:
Cystine produces a disulfide bridge, which is formed when two cysteine molecules are joined by covalent bonds. The residues are normally 5 to 6 residues apart.
As a result, when a novel medication is being developed selectively cleaves covalent connections between non-adjacent sulfur atoms in a polypeptide chain, it cleaves the primary interaction sustaining the Tertiary structure which is the disulfide bridge. As a result, this medicine affects the tertiary structure of the protein.
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