Advantages and disadvantages of low shear granulation
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shear granulation is a shaping process for granulation that has been enhanced for application in the pharmaceutical industry. A binder liquid is fed to the powder particles in a closed container with blending tools and a chopper.
Advantage-
Granulation process requires less binder solution.
Granulation is achieved within a short time.
Disadvantage-
High-shear granulator produces less compressible granules when compared to low-shear granulator.
It has a narrow range of operating conditions.
Over wetting of the granules may lead to formation of large sized lumps.
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