Amino acids which are specified by single codons are
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Tryptophan is unique because it is the only amino acid specified by a single codon.
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Most of the amino acids in the genetic code are encoded by at least two codons. In fact, methionine and tryptophan are the only amino acids specified by a single codon. Importantly, the reverse isn't true: each codon specifies just one amino acid or stop signal.
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