Question

Ammonia is an effective important urinary buffer for which of the following reasons ​

Answer 1

Answer:

When acidosis exists, the tubular cells secrete ammonia into the tubular fluid once the normal urinary phosphate buffers are saturated. Phosphate is the most important buffer in urine because its pKa is relatively close to the pH of glomerular filtrate and because the concentration of phosphate increases 20 fold.